Frank Tacke Selected Research

Liver Cirrhosis (Hepatic Cirrhosis)

10/2022	Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease - novel insights into cellular communication circuits.
7/2022	Shear wave elastography-based liver fibrosis assessment in patients with chronic hepatitis E displays elevated liver stiffness regardless of previous antiviral therapy.
6/2022	Combined Therapy with a CCR2/CCR5 Antagonist and FGF21 Analogue Synergizes in Ameliorating Steatohepatitis and Fibrosis.
4/2022	Soluble Urokinase Plasminogen Activator Receptor Levels Are Associated with Severity of Fibrosis in Patients with Primary Sclerosing Cholangitis.
2/2022	[Management of acutely decompensated liver cirrhosis in emergency and critical care medicine].
1/2022	[Management of acutely decompensated liver cirrhosis in emergency and critical care medicine].
7/2021	The APAC Score: A Novel and Highly Performant Serological Tool for Early Diagnosis of Hepatocellular Carcinoma in Patients with Liver Cirrhosis.
6/2021	Impact of spontaneous splenorenal shunt on liver volume and long-term survival of liver cirrhosis.
4/2021	Non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH)-related liver fibrosis: mechanisms, treatment and prevention.
2/2021	From Liver Cirrhosis to Cancer: The Role of Micro-RNAs in Hepatocarcinogenesis.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Frank Tacke Research Topics

Disease

102	Inflammation (Inflammations) 10/2022 - 06/2003
92	Fibrosis (Cirrhosis) 11/2022 - 04/2002
82	Liver Cirrhosis (Hepatic Cirrhosis) 10/2022 - 06/2002
66	Neoplasms (Cancer) 06/2022 - 05/2010
60	Liver Diseases (Liver Disease) 10/2022 - 04/2002
52	Critical Illness (Critically Ill) 12/2021 - 08/2008
46	Sepsis (Septicemia) 08/2021 - 08/2008
35	Infections 01/2022 - 04/2002
30	Non-alcoholic Fatty Liver Disease 10/2022 - 01/2014
30	Hepatocellular Carcinoma (Hepatoma) 10/2022 - 04/2003
15	Fatty Liver 06/2022 - 05/2005
14	Liver Neoplasms (Liver Cancer) 11/2021 - 05/2010
14	Hepatitis 01/2021 - 04/2002
11	Obesity 06/2022 - 01/2009
11	Insulin Resistance 04/2021 - 05/2005
10	Disease Progression 01/2022 - 08/2007
10	Hemorrhage 10/2021 - 04/2003
9	Alcoholic Fatty Liver 06/2022 - 03/2012
9	Hepatitis C 01/2022 - 01/2010
9	COVID-19 01/2022 - 01/2020
9	Hepatitis B 01/2019 - 04/2002
8	Neoplasm Metastasis (Metastasis) 10/2021 - 04/2016
8	Acute Liver Failure (Fulminant Hepatic Failure) 01/2018 - 04/2008
7	Renal Insufficiency (Renal Failure) 01/2019 - 01/2009
7	Necrosis 07/2018 - 12/2011
6	Sclerosing Cholangitis 04/2022 - 01/2017
6	End Stage Liver Disease 03/2022 - 06/2006
6	Neuroendocrine Tumors (Neuroendocrine Tumor) 08/2021 - 06/2019
6	Portal Hypertension 06/2021 - 07/2003
6	Colitis 07/2018 - 09/2008
5	Cholangiocarcinoma 06/2022 - 01/2016
5	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 01/2022 - 01/2011
5	Type 2 Diabetes Mellitus (MODY) 01/2022 - 01/2009
5	Atherosclerosis 10/2021 - 03/2006
5	Chronic Hepatitis B 01/2021 - 08/2004
4	Chronic Hepatitis C 01/2022 - 02/2008
4	Reperfusion Injury 10/2021 - 06/2003
4	Pancreatic Neoplasms (Pancreatic Cancer) 06/2021 - 07/2018
4	Cholestasis 01/2021 - 05/2005
4	Communicable Diseases (Infectious Diseases) 09/2019 - 01/2014

Drug/Important Bio-Agent (IBA)

72	Biomarkers (Surrogate Marker)IBA 06/2022 - 07/2003
36	CytokinesIBA 01/2021 - 09/2008
31	ChemokinesIBA 01/2022 - 11/2006
24	Chemokine ReceptorsIBA 06/2022 - 03/2006
21	Proteins (Proteins, Gene)FDA Link 01/2022 - 04/2007
20	LigandsIBA 11/2022 - 08/2007
19	MicroRNAs (MicroRNA)IBA 01/2022 - 01/2011
14	Antiviral Agents (Antivirals)IBA 07/2022 - 06/2014
13	Pharmaceutical PreparationsIBA 06/2022 - 08/2004
13	Urokinase Plasminogen Activator ReceptorsIBA 04/2022 - 01/2011
12	CollagenIBA 01/2021 - 09/2009
11	Interleukin-6 (Interleukin 6)IBA 01/2021 - 07/2003
10	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 05/2007
9	Choline (Choline Chloride)IBA 06/2022 - 01/2014
9	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2016
9	InterferonsIBA 01/2021 - 10/2004
9	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021 - 06/2006
9	Carbon Tetrachloride (Tetrachloromethane)IBA 01/2019 - 11/2010
8	Immune Checkpoint InhibitorsIBA 03/2021 - 06/2020
8	AdipokinesIBA 12/2019 - 05/2007
8	Methionine (L-Methionine)FDA Link 01/2019 - 01/2014
7	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 10/2022 - 12/2014
7	cenicrivirocIBA 01/2022 - 01/2018
7	OsteopontinIBA 08/2021 - 01/2015
7	AdiponectinIBA 12/2019 - 05/2005
6	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 06/2022 - 02/2011
6	CC ChemokinesIBA 01/2022 - 08/2007
6	Messenger RNA (mRNA)IBA 09/2021 - 06/2002
6	C-Reactive ProteinIBA 03/2021 - 06/2006
6	Hepatitis B Surface Antigens (HBsAg)FDA Link 01/2021 - 04/2007
6	Peptides (Polypeptides)IBA 01/2020 - 04/2012
6	ResistinIBA 12/2019 - 06/2006
5	LipidsIBA 10/2022 - 10/2016
5	Triglycerides (Triacylglycerol)IBA 06/2022 - 03/2012
5	AntibodiesIBA 01/2022 - 01/2017
5	Bile Acids and Salts (Bile Acids)IBA 01/2022 - 01/2018
5	Tumor Biomarkers (Tumor Markers)IBA 10/2021 - 05/2011
5	IntegrinsIBA 08/2021 - 12/2014
5	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 08/2006
4	Protein Kinases (Protein Kinase)IBA 10/2022 - 01/2016
4	Amino Acids FDA Link 06/2022 - 05/2020
4	6-propylchromone-2-carboxylic acid (PCCA)IBA 04/2022 - 08/2019
4	Insulin (Novolin)FDA Link 01/2022 - 04/2003
4	Dexamethasone (Maxidex)FDA LinkGeneric 01/2022 - 01/2015
4	Extracellular Matrix ProteinsIBA 04/2021 - 09/2009
4	Hepatitis B e AntigensIBA 01/2021 - 08/2004
4	Somatostatin Receptors (Somatostatin Receptor)IBA 01/2021 - 01/2020
4	AntigensIBA 01/2021 - 01/2014
4	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2020 - 01/2012
4	Retinol-Binding Proteins (Retinoid Binding Proteins)IBA 12/2019 - 05/2007
4	Liposomes (Liposome)IBA 01/2019 - 08/2014
4	Caspase 8 (Caspase-8)IBA 01/2017 - 12/2011
4	Apolipoproteins E (ApoE)IBA 08/2015 - 03/2006

Therapy/Procedure

74	Therapeutics 10/2022 - 10/2004
23	Liver Transplantation 06/2022 - 03/2006
12	Ligation 10/2021 - 05/2005
9	Critical Care (Surgical Intensive Care) 02/2022 - 01/2009
7	Transplantation 10/2022 - 02/2010
5	Immunotherapy 01/2021 - 10/2017
4	Drug Therapy (Chemotherapy) 05/2021 - 03/2018